Differential Outcomes Following 4 Weeks of Aclidinium/Formoterol in Patients with COPD: A Reanalysis of the ACTIVATE Study

Using the data from the ACTIVATE study, where the effect of long-acting bronchodilators (LABD) therapy on lung hyperinflation, exercise endurance and PA was studied, we aimed to identify multidimensional outcome patterns for LABD therapy in patients with COPD, including static and dynamic lung function measures, exercise performance and PA by performing a cluster analysis. Moreover, we aimed to determine the initial characteristics associated with these patterns.